| Gaps in the Field of Lymphatic Research | 2026–27 Update | 1 2026–27 Review prepared by the Lymphatic Education & Research Network (LE&RN) in collaboration with the Lymphatic Research Community for distribution to: Advance Research Projects Agency for Health (APRP-H) Alicia Jackson, Ph.D. Centers for Disease Control and Prevention–Chronic Disease Education and Awareness (CDC/CDEA) Captain Jacqueline Miller, MD, FACS National Heart, Lung, Blood Institute (NHLBI) Strategic Vision Refresh David C. Goff, M.D., Ph.D., Acting Director National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Lindsey A. Criswell, M.D., M.P.H., D.Sc. National Institutes of Health (NIH) National Commission for Lymphatic Diseases Jay Bhattacharya, M.D., Ph.D. Peer-Reviewed Medical Research Program (PRMRP)/ Congressionally Directed Medical Research Program (CDMRP) at US Army Kathryn Argue, Ph.D. Since 1998, the mission of the Lymphatic Education & Research Network (LE&RN) has been to fight lymphatic diseases through education, research, and advocacy. We seek to accelerate the prevention, treatments, and cures for lymphedema, lipedema, lymphatic anomalies, and the continuum of lymphatic diseases. The lymphatic research field is at a turning point. For the first time in history, four federal public health agencies are focused on lymphatic biology and disease. These agencies and their leaders can take an unprecedented leap toward revolutionizing global health through their individual and collaborative actions. The LE&RN community looks forward to playing its role in facilitating the communication between researchers and federal agencies to this end. —William Repicci, President & CEO We thank the global lymphatic research community who collaborated to create this document. We also thank the National Institutes of Health, who hosted the 2022 research workshop, Yet to Be Charted: Lymphatic System in Health and Disease, and all of the presenters who identified knowledge gaps and opportunities in lymphatic disease research that are included in this document.
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