Latest Research

Latest Research

Since its beginnings in 1988, LE&RN has been at the forefront of research into lymphedema and lymphatic disease. We know that lymphatic research is vital for all of us, holding the key to unraveling diseases such as AIDS, diabetes, heart disease, rheumatoid arthritis, cancer, obesity, auto-immune diseases, lupus, and many others. Below are some of the latest studies to be conducted on the lymphatic system.


  • Effect of Lymphaticovenous Anastomosis on Muscle Edema, Limb, and Subfascial Volume in Lower Limb LE Effect of Lymphaticovenous Anastomosis on Muscle Edema, Limb, and Subfascial Volume in Lower Limb LE
  • The centuries long pursuit to map the human lymphatic system The centuries long pursuit to map the human lymphatic system
  • Intracellular calcium dynamics of lymphatic endothelial and muscle cells Intracellular calcium dynamics of lymphatic endothelial and muscle cells
  • A Comparison of Bioimpedance Spectroscopy or Tape Measure Triggered Compression Intervention A Comparison of Bioimpedance Spectroscopy or Tape Measure Triggered Compression Intervention
  • Lymphangion-chip Lymphangion-chip
  • The impact of monitoring techniques on progression to chronic breast cancer‑related lymphedema The impact of monitoring techniques on progression to chronic breast cancer‑related lymphedema
  • Detection of NRAS mutation in cell-free DNA biological fluids from patients with kaposiform lymphang Detection of NRAS mutation in cell-free DNA biological fluids from patients with kaposiform lymphang
  • Kaposiform lymphangiomatosis treated with multimodal therapy improves coagulopathy and reduces blood Kaposiform lymphangiomatosis treated with multimodal therapy improves coagulopathy and reduces blood
  • Effect of Pneumatic Compression Therapy on lymph movement in LE-affected extremities Effect of Pneumatic Compression Therapy on lymph movement in LE-affected extremities
  • NIRFLI* to Reconsider Occlusion Pressure of Superficial Lymphatic Collectors in Upper Extremities… NIRFLI* to Reconsider Occlusion Pressure of Superficial Lymphatic Collectors in Upper Extremities…