Clinical Trials and Studies
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ILF International Survey for US Therapists, Patients, and Industry Partners
From the International Lymphoedema Framework and on behalf of the American Lymphedema Framework Project:
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Patient, Professional, Industry Partner? Your input is important! Help us understand the effects of lymphoedema treatment and to set international standards for outcome measures for patients with chronic edema. Take a few minutes and complete the ILF-COM survey -> https://www.surveymonkey.com/r/CYSCKKT
The survey is open until March 31. Read more about ILF-COM project here -> http://www.lympho.org/chronic-oedema-outcome-measure -
BIDMC Acupuncture for Breast Cancer Related Lymphedema StudyResearchers at Beth Israel Deaconess Medical Center in Boston, MA are conducting a study to demonstrate the feasibility and effectiveness of acupuncture for patients with breast cancer related lymphedema.
You may be eligible for this study if you have a single arm affected by lymphedema following breast cancer treatment.
Participants will be paid $50 for their time and will receive acupuncture treatments free of charge.The study length is 6 weeks.
All prospective study subjects who are not current patients of the lymphedema treatment clinic at BIDMC must first be evaluated by Dr. Singhal to assess if they are appropriate candidates for the study (a comprehensive lymphedema evaluation) and then have clinical measurements taken by a certified lymphedema therapist. (These two appointments are outside of the study).
There are a total of 12 acupuncture sessions which take place over a 6-week period. Acupuncture sessions generally begin 1-2 weeks after a patient has had their baseline evaluation (lab work and clinical measurements). Clinical measurements are repeated at week 3 (midpoint) of the study. At the end of the study (week 6), participants have clinical measurements and bloodwork taken.
There are two study groups (all patients are offered 12 acupuncture sessions regardless of initial group assigned!)—one group receives 12 acupuncture sessions right away during this 6 week period (after baseline evaluation), and the other group is monitored clinically for 6-weeks, but then receives their 12 acupuncture treatments after that time period.
All parking-related costs are reimbursed by the study.Please contact the study team to find out more or to see if you are eligible:
Dhruv Singhal, MD
Email address: lymphaticsurgery@bidmc.harvard.edu
Phone Number: 617-632-7855 -
Vanderbilt Lymphedema/Lipedema MRI StudyVolunteers Needed for Lymphedema and Lipedema Research Study
We are ENROLLING women who
-have lymphedema in a leg following cancer treatment
-are comfortable in an MRI scannerThe purposes of this study are
-to investigate the potential of MRI serving as a diagnostic tool for lipedema
-to better understand the tissue composition of legs with secondary lymphedema
-to better comprehend how lymphedema and lipedema effect the lymphatic systemThe study is a one-time visit of 3 hours and involves an MRI scan of the body. Volunteers will be appropriately compensated for participating in the study. If you are interested in further information, please email INFORM@vumc.org or call 615-343-2011.
Study Site Location: Nashville, TN
Vanderbilt University Institute of Imaging Science
1161 21st Ave S AA-1105, Nashville, TN 37232This research study is funded in part by grant support from the Lymphatic Education & Research Network and the Lipedema Foundation.
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University of California San Francisco (UCSF) Breast Cancer Related Lymphedema Treatment StudyResearchers at UCSF are conducting a study to learn if treatment with a negative pressure massage device (Lymphatouch) is effective, compared to manual lymphatic drainage (MLD) massage, at improving swelling, skin condition, and movement in the arms of women with lymphedema.
You may be able to take part in this study if you:
* Have had lymphedema in one arm for at least one year
* Your lymphedema has not changed significantly in the last 3 monthsParticipants will be paid $50 for their time, have parking and bridge toll reimbursed, and will receive 12 massage treatments (2 to 3 times a week for 4 to 6 weeks) for their lymphedema arm!
Please contact the study investigator to find out more or to see if you are eligible:
Betty Smoot, PT, DPTSc
707-494-8262
Betty.Smoot@ucsf.edu
PhysioTouch@ucsf.edu -
Breast Cancer Survivor Study
Vanderbilt University School of Nursing is looking for female breast cancer survivors over the age of 18. Participation in the study involves filling out surveys. Download a flyer here.
If interested, please contact Melissa at 615-343-6313 or lymphresearch@vanderbilt.edu.
Learn More > -
ULTRA: A Phase 2 Study of the Investigational Medication Ubenimex in Lymphedema
ULTRA is Ubenimex in adult patients with Lymphedema of The lower limb: a Phase 2, RAndomized, double-blind, placebo-controlled study of efficacy, safety, and pharmacokinetics.
This study is being expanded to include both patients with primary lymphedema not of congenital onset, as well as secondary lymphedema.
Eligible patients must have a diagnosis of leg lymphedema and must have completed a full course of complete decongestive therapy (CDT) at least 4 weeks prior to screening, including use of compression garments for at least 4 weeks without change in regimen. Patients must also be willing to maintain a stable regimen of self-care, including use of compression garments from screening through the entire study duration (through the safety follow-up visit).Approximately 40 patients will be enrolled in the ULTRA study and will be randomized in a 1:1 ratio to receive ubenimex three times a day or TID (20 patients) or placebo three times a day or TID (20 patients) for 24 weeks.
Inquiries to participate should be directed to:
• Stanford University, Leslie Roche, RN, BSN (lesroche@stanford.edu, 650-723-1396)
• University of Florida Health Cancer Center at Orlando Health, Jennifer Quintiliani, RN, CCRP (Jennifer.quintiliani@orlandohealth.com, 321-843-2026)
• The Ohio State University, Columbus, Filiz Muharrem (filiz.muharrem@osumc.edu, 614-366-5844)To see if you may qualify to participate in this study please visit www.eigerLE.com or call 1-877-899-2051. This study is being sponsored by Eiger BioPharmaceuticals (www.eigerbio.com). For a complete description of the study, please go to clinicaltrials.gov (NCT02700529).
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University of California San Francisco (UCSF) Breast Cancer Related Lymphedema StudyUCSF researcher Christine Miaskowski, RN, PhD and colleagues are conducting a research study to learn more about the signs and symptoms of lymphedema associated with breast cancer treatments. Lymphedema is the swelling in the arms, shoulders, hands and/or breast area as a result of breast cancer treatment. The team also wants to know if there are genetic, (i.e., inherited) factors that predict whether patients develop lymphedema or not.
To be eligible to participate in the Risk Factors of Breast Cancer Lymphedema Study, you must:• Be female, at least 18 years old
• Have had breast cancer on one side only
• Completed surgery for breast cancer & any other breast cancer treatment (radiation and chemotherapy) at least 6 months ago
• Have a diagnosis of breast cancer treatment-related lymphedemaParticipants will complete online questionnaires and have a one-time study visit to UCSF, Parnassus campus. Participants will be paid $150 for their time and travel.
To find out if you qualify or for other questions, contact the study research team at 855-855-UCSF (855-855-8273) toll free or email Judy Mastick, RN, study project director, at symptoms@ucsf.edu.
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Systemic Therapy to Treat Lymphatic Malformations
Clinical Trial at Stanford School of Medicine:
Dr. Joyce Teng, MD, PhD at Stanford University School of Medicine, CA is conducting a clinical trial on the use of Sildenafil treatment for patients ages 6 months - 10 years of age with Lymphatic Malformations (LM).
Participation involves visits to Stanford, as well as at local sub-sites being conducted in Chicago, IL, and Denver, Colorado. Duration is 20 - 52 weeks. There is no compensation for this study, but all travel is covered by Stanford. A separate study is also being conducted, which involves genetic testing of patients with lymphatic malformations.
To find out more information or to see if your child qualifies, please contact Elidia Tafoya, MPH, study coordinator, at 650-724-1982 or by email at etafoya@stanford.edu. To view clinical study flyer, click here.
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Stanford Fibralign Biobridge Lymphedema StudyFor women and men who have lymphedema of the arm, there is a growing interest in lymph node transfer as a surgical solution. Dr. Stanley G. Rockson and his research team at Stanford University are currently studying lymph node transfer for arm lymphedema, to determine the best possible approaches for a favorable outcome to the surgery. If you have arm lymphedema and are contemplating lymph node transfer surgery, you may be eligible to participate in this study. For more information, please call Eric Henderson at 650-723-1396 or e-mail ehenders@stanford.edu.
For general information about participant rights, contact: 1-866-680-2906.
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Study for children with lymphedema
Parents of children who have been diagnosed with lymphedema are invited to participate in a research study at Miami University (Ohio). The purpose of this study is to better understand the experiences of biological parents of children with lymphedema.
They are interested in learning more from you about what it is like for you in caring for a child with primary lymphedema. Specifically, they want to know about your unique challenges as a parent, your role as an advocate for their child in health care, school-based, and other settings, how you explain lymphedema to your children and how you help your children in turn explain lymphedema to others.
Volunteers will participate in an informal interview over the telephone, via video conference (e.g, FaceTime, Skype, Google Hangout), or face-to-face with an interviewer. The interview may last up to one hour
This study has been approved by the Miami University Institutional Review Board: 01182r.
If you would like to participate in this opportunity, please contact the Principal Investigator:
Elise Radina, PhD, CFLE
Professor and Acting Chair
Family Studies & Social Work
Miami UniversityRadinaME@MiamiOH.edu
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