LE&RN Centers of Excellence (COE) in the Diagnosis and Treatment of Lymphatic Diseases (LD) have been designed to increase access to the best possible multi-disciplinary clinical care and services for individuals affected by LD and their families through a geographically diverse network of local and/or regional clinical centers. In addition to clinical and social services, the Centers will provide professional and lay education in the geographic areas they serve, are involved in LD clinical research, and work with LE&RN locally and internationally in its efforts to continually improve the lives of those affected by LD and their families. Applications to become a LE&RN Center of Excellence are open to institutions globally on an annual basis. These Centers share LE&RN’s commitment to quality care and are committed to a team approach of working with LE&RN and Patient Affiliate Boards to continually monitor and improve care. Those institutions awarded a LE&RN Center of Excellence designation are subject to an extensive review process described in the Centers of Excellence Program Application. See below for the five categories of Centers of Excellence designations and the institutions awarded a designation.